Endocrine Abstracts

Introduction: Riedel’s thyroiditis, also known as invasive fibrous thyroiditis, is a rare disorder of unknown etiology in which characterized by invasive fibrosis that partially destroys the thyroid gland and extends into adjacent neck structures. The diagnosis of Riedel’s thyroiditis is clinically difficult because this form of thyroiditis can mimic lymphoma or Hashimoto’s thyroiditis during preoperative radiologic, and pathologic examination. Sonographic featu...

The most common reason for the rare condition of hyperinsulinemia-related hypoglycaemia is insulinoma, a tumor of pancreatic islet cells. However, nesidioblastosis characterized by diffuse or focal hyperplasia of the pancreatic islet cells is the most common cause of hyperinsulinemic hypoglycemia in newborns. Nesidioblastosis seen in newborns is now called ‘persistent hyperinsulinemic hypoglycemia of infancy’ (PHHI) while the condition in adults is called ‘nonin...

Dopamine agonists are the treatment of choice for prolactinomas and surgery is warranted only when the response to medical therapy is poor, not tolerated, or in those with compromised vision or with extensive invasion. We describe the two cases of a giant prolactinoma treated with cabergoline alone and next to surgery and gamma-knife.Case 1: A 30-year-old man admitted with headache and visual defect, cranial magnetic resonance imaging (MRI) revealed a in...

Introduction: The involvement of certain organs such as the adrenal gland is rare in non-Hodgkin’s lymphoma (NHL). Although lymphomas can involve virtually all extranodal organs, different organs show different frequency of involvement. Adrenal gland involvement is usually bilateral. We report that a rare case of unilateral adrenal involvement of diffuse large B-cell lymphoma presenting with abdominal pain.Case: A 64-year-old-man presented with abdo...

Case: A 75-year-old male patient was treated for lung adenocarcinoma 12 years ago. During the routine imaging studies of the patient who was followed without treatment after curing, a suspicious, non-adenomatous lesion in the right adrenal gland, 16×9 mm in size was detected by thoracic computed tomography. Serum aldosterone/renin ratio and urine catecholamine tests were normal with no complaints of suspicion for pheochromocytoma. F18FDG PET-CT showed an increase in metab...

A 27-year-old woman with had sweating flushing attacks for three years prior to pregnancy, but did not follow with any medical examination. At 12th gestational week, hypertension was detected and alpha-methyldopa was started, no abnormal findings were found in the routine examinations, in the 24-h holter study, blood pressure values (using alpha-methyldopa) were found to be higher than 144/99 (general), 147/101 (awake) and 134/92 mmHg (sleep). 24-hour urinary levels of catecho...

A 60-year-old male patient who presented with left hip and knee pain was found to be compatible with primary hyperparathyroidism (PTH:2233 pg/ml, calcium: 15.7 mg/dl, phosphorus: 2.9 mg/dl creatinin:1.99 mg/dl, 25-OH-D:9.7 μg/l, ALP:532 mU/ml). Bone grafts of the patient showed multiple lytic lesions in the pelvis, cranium and long-bones. Neck ultrasonography showed hypoechoic solid nodule with cystic areas, 2×2 cm with size in the left thyroid gland inferior region ...

Background: Sitagliptin, unlike the some major antihyperglycemic drugs, is not associated with weight gain and has neutral effects on body weight. It is unclear whether sitagliptin treatment alters immune functions and insulin resistance in people with type 2 diabetes. The aim of the present study was to assess the effect of sitagliptin on insulin resistance and immune functions in patients with type 2 diabetes mellitus.Methods: Twenty type 2 diabetic su...

Introduction: Hyalinizing trabecular adenomas (HTA) of the thyroid gland is a rare neoplasm of follicular cell origin. HTA can be present as a thyroid nodule or incidental finding in a thyroidectomy specimen. HTA is generally accepted to be a benign tumor, but their cytological features can be similar to those of papillary thyroid carcinoma (PTC).Case report: A 59 year old woman, who had cholangiocellular carcinoma, admitted to our institution with a sol...

Aim: Delayed gastric emptying affects a substantial proportion of patients with long-standing diabetes. On the other hand changes in gastric incretin hormones also play an important role in the pathophysiology of diabetes. In our study, we aimed to investigate the incidence of gastrointestinal disease in patients with newly diagnosed diabetes and pre-diabetes.Methods: A total of 73 patients with newly diagnosed pre-diabetes and diabetes were included in ...